Juvenescence

Investing in the age of longevity

Author: Jim Mellon,Al Chalabi

Publisher: Harriman House Limited

ISBN: 0993047823

Category: Business & Economics

Page: 438

View: 7195

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Juvenescence

Investing in the Age of Longevity

Author: Jim Mellon,Al Chalabi

Publisher: N.A

ISBN: 9780993047817

Category: Aging

Page: 250

View: 8990

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This new book by Jim Mellon and Al Chalabi is a layman's guide to longevity. It investigates the new technologies and explains how to benefit from the life extending technologies both personally and professionally. It helps readers unravel the science, offers ideas on potential investment and reveals the views of the key opinion leaders.

Cracking the Code

Understand and Profit from the Biotech Revolution That Will Transform Our Lives and Generate Fortunes

Author: Jim Mellon,Al Chalabi

Publisher: John Wiley & Sons

ISBN: 1119969379

Category: Business & Economics

Page: 320

View: 6681

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Everything you need to know about the most important trend in the history of the world Within most people's lifetimes, the developments in the biotechnology sector will allow us to live increasingly long and healthy lives, as well as provide us with technological innovations that will transform the way we live. But these innovations offer more than just hope for a better life, but hope for better returns too. Financial returns of incredible magnitude await savvy investors and businesspeople who can see the massive changes on the horizon. This book details these fast-moving trends and innovations and offers extensive advice on how to profit from them in business and investing.

Ending Aging

The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

Author: Aubrey de Grey,Michael Rae

Publisher: St. Martin's Press

ISBN: 9781429931830

Category: Science

Page: 400

View: 9147

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MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Wake Up!

Survive and Prosper in the Coming Economic Turmoil

Author: Jim Mellon,Al Chalabi

Publisher: Capstone

ISBN: 9781841126913

Category: Business & Economics

Page: 300

View: 7853

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'This book is a dramatic wake-up call to investors. It portrays an apocalyptic future of high risk and low rewards. It is well informed and highly readable. While some may dispute the author's bleak vision, this is nevertheless required reading for anyone who wants to understand the massive changes hitting the world's economies in the coming decades.' Luke Johnson, Chairman of Channel 4 and Signature Restaurants and Columnist for The Sunday Telegraph. 'This book is a compelling recital of serious points upon which all citizens, whether professional investors or not, will have to make up their mind.' Simon Cawkwell (aka "Evil Knievil", leading British Bear). 'If you are not yet worried about the financial future you should be. The global economy isn't as healthy as you think it is. Wake Up! explains why and then tells you exactly what to do about it. A brilliantly written and very convincing financial horror story. A must read for anyone who wants to preserve their capital over the coming decade.' Merryn Somerset-Webb, Editor of MoneyWeek and Sunday Times Columnist.

The 100-Year Life

Living and Working in an Age of Longevity

Author: Lynda Gratton,Andrew Scott

Publisher: Bloomsbury Publishing

ISBN: 1472930169

Category: Business & Economics

Page: 256

View: 2633

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What will your 100-year life look like? Does the thought of working for 60 or 70 years fill you with dread? Or can you see the potential for a more stimulating future as a result of having so much extra time? Many of us have been raised on the traditional notion of a three-stage approach to our working lives: education, followed by work and then retirement. But this well-established pathway is already beginning to collapse – life expectancy is rising, final-salary pensions are vanishing, and increasing numbers of people are juggling multiple careers. Whether you are 18, 45 or 60, you will need to do things very differently from previous generations and learn to structure your life in completely new ways. The 100-Year Life is here to help. Drawing on the unique pairing of their experience in psychology and economics, Lynda Gratton and Andrew Scott offer a broad-ranging analysis as well as a raft of solutions, showing how to rethink your finances, your education, your career and your relationships and create a fulfilling 100-year life. · How can you fashion a career and life path that defines you and your values and creates a shifting balance between work and leisure? · What are the most effective ways of boosting your physical and mental health over a longer and more dynamic lifespan? · How can you make the most of your intangible assets – such as family and friends – as you build a productive, longer life? · In a multiple-stage life how can you learn to make the transitions that will be so crucial and experiment with new ways of living, working and learning? Shortlisted for the FT/McKinsey Business Book of the Year Award, The 100-Year Life is a wake-up call that describes what to expect and considers the choices and options that you will face. It is also fundamentally a call to action for individuals, politicians, firms and governments and offers the clearest demonstration that a 100-year life can be a wonderful and inspiring one.

The Youth Pill

Scientists at the Brink of an Anti-Aging Revolution

Author: David Stipp

Publisher: Penguin

ISBN: 110144228X

Category: Business & Economics

Page: 336

View: 8519

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In The Youth Pill, journalist David Stipp explores the scientific battle against aging and the pioneers of the movement to extend lifespan for everyone. He takes readers behind the scenes and introduces us to the key players who are experimenting with the most promising cutting-edge research. It is an informative and provocative read that shows how a small group of optimistic and determined scientists are closing in on drugs that will change the way we live forver.

The Ageless Generation

How Advances in Biomedicine Will Transform the Global Economy

Author: Alex Zhavoronkov

Publisher: Macmillan

ISBN: 0230342205

Category: Science

Page: 233

View: 5082

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An assessment of recent advances in biomedical science evaluates their potential role in shaping the future of health care, retirement and the global economy, examining innovations in regenerative medicine that may significantly extend longevity and productivity, enable breakthroughs in organ replacement and more. 30,000 first printing.

Juvenescence

A Cultural History of Our Age

Author: Robert Pogue Harrison

Publisher: University of Chicago Press

ISBN: 022617199X

Category: History

Page: 215

View: 9298

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Argues that humanity is growing steadily younger, as society retains more physical and mental characteristics of youth, which is a luxury required for flashes of genius and innovative drive.

Anti-aging Drugs

From Basic Research to Clinical Practice

Author: Alexander M Vaiserman

Publisher: Royal Society of Chemistry

ISBN: 1782629858

Category: Medical

Page: 570

View: 7740

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Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.

The Longevity Economy

Unlocking the World's Fastest-Growing, Most Misunderstood Market

Author: Joseph F. Coughlin

Publisher: PublicAffairs

ISBN: 1610396650

Category: Business & Economics

Page: 352

View: 342

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Oldness: a social construct at odds with reality that constrains how we live after middle age and stifles business thinking on how to best serve a group of consumers, workers, and innovators that is growing larger and wealthier with every passing day. Over the past two decades, Joseph F. Coughlin has been busting myths about aging with groundbreaking multidisciplinary research into what older people actually want--not what conventional wisdom suggests they need. In The Longevity Economy, Coughlin provides the framing and insight business leaders need to serve the growing older market: a vast, diverse group of consumers representing every possible level of health and wealth, worth about $8 trillion in the United States alone and climbing. Coughlin provides deep insight into a population that consistently defies expectations: people who, through their continued personal and professional ambition, desire for experience, and quest for self-actualization, are building a striking, unheralded vision of longer life that very few in business fully understand. His focus on women--they outnumber men, control household spending and finances, and are leading the charge toward tomorrow's creative new narrative of later life--is especially illuminating. Coughlin pinpoints the gap between myth and reality and then shows businesses how to bridge it. As the demographics of global aging transform and accelerate, it is now critical to build a new understanding of the shifting physiological, cognitive, social, family, and psychological realities of the longevity economy.

Top Ten Investments to Beat the Crunch!

Invest Your Way to Success even in a Downturn

Author: Jim Mellon,Al Chalabi

Publisher: John Wiley & Sons

ISBN: 9781907293726

Category: Business & Economics

Page: 248

View: 5889

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Everyone has it within them to become a successful investor. Right here's where you start. Ignore the doom and gloom merchants - now is the time to start investing for the future. Bestselling authors Jim Mellon and Al Chalabi were seen as the party poopers just a few years ago when they predicted the financial crisis in Wake Up! Now they take the opposite view - the party is about to start. It won't last forever, but in a few years a lot of money can be made by the astute and well-informed. This is your step-by-step introduction to the world of investment - including all the BigIdeas seasoned investors are searching for. You'll pick up ingenious and lucrative investment ideas in: Real Estate Stocks and Mutual Funds Bonds and Cash The BRIC Economies Commodities and Collectibles Green Investments "The DIY manual for building lasting wealth." —Ross O'Brien, The Economist Group "Packed with wise, practical advice, this book puts into plain English what every investor needs to know." —The Financial Times "…the book's main benefit was to show me that the mysteries of investment… lie within my grasp." —Financial World "...a timely, practical reminder that it's never too late to start investing for tomorrow." —moneyextra.com "…the advice in this book will beat most professional fund managers by leaps and bounds." —Sven Lorenz, market commentator, author & investor, and columnist for Money Week Please note: this book is the paperback edition of Jim and Al's Top 10 Investments for the Next 10 Years.

Selling the Fountain of Youth

How the Anti-Aging Industry Made a Disease Out of Getting Old-And Made Billions (Large Print 16pt)

Author: Arlene Weintraub

Publisher: ReadHowYouWant.com

ISBN: 1458732304

Category:

Page: 308

View: 6054

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The beauty industry-which once revolved around creams and powders, subtle agents to enhance beauty-has become the anti-aging industry, overrun with steroids, human growth hormone injections, and ''bio-identical'' hormones-all promoted as ''cures'' for getting old. Acclaimed BusinessWeek science reporter Arlene Weintraub takes us inside this world, from the marketing departments of huge pharmaceutical companies to the backroom of your local pharmacy, from celebrity enthusiasts like Suzanne Somers and Oprah to the self-medicating doctors who run chains of rejuvenation centers, all claiming that we deserve to be forever young-and promising to show us how.Weintraub reveals the shady practices that run rampant when junk science and dubious marketing meet consumer choice. She shows for the remarkable economic and cultural impact of anti-aging medicine, on the patients who partake and on the rest of us. It's not a pretty story, but Weintraub tells us everything we need to know to avoid being duped by this billion-dollar-and dangerous-hoax.

The Longevity Seekers

Science, Business, and the Fountain of Youth

Author: Ted Anton

Publisher: University of Chicago Press

ISBN: 0226020959

Category: Science

Page: 224

View: 4026

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People have searched for the fountain of youth everywhere from Bimini to St. Augustine. But for a steadfast group of scientists, the secret to a long life lies elsewhere: in the lowly lab worm. By suppressing the function of just a few key genes, these scientists were able to lengthen worms’ lifespans up to tenfold, while also controlling the onset of many of the physical problems that beset old age. As the global population ages, the potential impact of this discovery on society is vast—as is the potential for profit. With The Longevity Seekers, science writer Ted Anton takes readers inside this tale that began with worms and branched out to snare innovative minds from California to Crete, investments from big biotech, and endorsements from TV personalities like Oprah and Dr. Oz. Some of the research was remarkable, such as the discovery of an enzyme in humans that stops cells from aging. And some, like an oft-cited study touting the compound resveratrol, found in red wine—proved highly controversial, igniting a science war over truth, credit, and potential profit. As the pace of discovery accelerated, so too did powerful personal rivalries and public fascination, driven by the hope that a longer, healthier life was right around the corner. Anton has spent years interviewing and working with the scientists at the frontier of longevity science, and this book offers a behind-the-scenes look at the state-of-the-art research and the impact it might have on global public health, society, and even our friends and family. With spectacular science and an unforgettable cast of characters, The Longevity Seekers has all the elements of a great story and sheds light on discoveriesthat could fundamentally reshape human life.

The Volatility Machine

Emerging Economies and the Threat of Financial Collapse

Author: Michael Pettis

Publisher: Oxford University Press on Demand

ISBN: 9780195143300

Category: Business & Economics

Page: 245

View: 7462

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This book presents a radically different argument for what has caused, and likely will continue to cause, the collapse of emerging market economies. Pettis combines the insights of economic history, economic theory, and finance theory into a comprehensive model for understanding sovereign liability management and the causes of financial crises. He examines recent financial crises in emerging market countries along with the history of international lending since the 1820s to argue that the process of international lending is driven primarily by external events and not by local politics and/or economic policies. He draws out the corporate finance implications of this approach to argue that most of the current analyses of the recent financial crises suffered by Latin America, Asia, and Russia have largely missed the point. He then develops a sovereign finance model, analogous to corporate finance, to understand the capital structure needs of emerging market countries. Using this model, he finally puts into perspective the recent crises, a new sovereign liability management theory, the implications of the model for sovereign debt restructurings, and the new financial architecture. Bridging the gap between finance specialists and traders, on the one hand, and economists and policy-makers on the other, The Volatility Machine is critical reading for anyone interested in where the international economy is going over the next several years.

Against Everything

Essays

Author: Mark Greif

Publisher: Vintage

ISBN: 1101971746

Category: Literary Collections

Page: 320

View: 5245

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Over the past eleven years, Greif has been publishing superb, and in some cases already famous, essays in n+1, the high-profile little magazine that he co-founded. These essays address such key topics in the cultural, political, and intellectual life of our time as the tyranny of exercise, the tyranny of nutrition and food snobbery, the sexualization of childhood (and everything else), the philosophical meaning of Radiohead, the rise and fall of the hipster, the impact of the Occupy Wall Street movement, and the crisis of policing. Four of the selections address, directly and unironically, the meaning of life--what might be the right philosophical stance to adopt toward one's self and the world. Each essay in Against Everything is learned, original, highly entertaining, and, from start to finish, dead serious. They are the work of a young intellectual who, with his peers, is reinventing and reinvigorating what intellectuals can be and say and do. Mark Greif manages to reincarnate and revivify the thought and spirit of the greatest of American dissenters, Henry David Thoreau, for our time and historical situation.--Publisher website.

How Flavor Works

The Science of Taste and Aroma

Author: Nak-Eon Choi,Jung H. Han

Publisher: John Wiley & Sons

ISBN: 1118865472

Category: Science

Page: 240

View: 4704

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Taste is the number one driving force in the decision to purchase a food product and food consumption is the most critical function for living organisms to obtain the energy and resources essential to their vitality. Flavor and aroma are therefore universally important concepts: intrinsic to human well-being and pleasure, and of huge significance for the multi-trillion dollar global food business. How Flavor Works: the Science of Taste and Aroma offers a fascinating and accessible primer on the concepts of flavor science for all who have an interest in food and related topics. Professionals and students of food science and technology who do not already specialize in flavor science will find it a valuable reference on a topic crucial to how consumers perceive and enjoy food products. In this regard, it will also be of interest to product developers, marketers and food processors. Other readers with a professional (eg culinary and food service) or personal interest in food will also find the book interesting as it provides a user-friendly account of the mechanisms of flavor and aroma which will provide new insights into their craft.

Advancing Conversations

Aubrey De Grey - Advocate For An Indefinite Human Lifespan

Author: Douglas Lain,Aubrey de Grey

Publisher: John Hunt Publishing

ISBN: 1785353977

Category: Social Science

Page: 80

View: 9052

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Advancing Conversations is a line of interview books documenting conversations with artists, authors, philosophers, economists, scientists, and activists whose works are aimed at the future and at progress. The biogerontologist Aubrey de Grey, as the world's pre-eminent longevity advocate, is nothing if not future oriented. De Grey is the founder of the SENS Research Foundation, an organization developing medical interventions to repair the damage the body does to itself over time. Stated more directly, Aubrey de Grey and his organization aim to defeat aging. In 2005 a panel of scientists and doctors from MIT, Brigham and Women's Hospital in Boston, Microsoft, and the Venter Institute participated in a contest to judge whether de Grey's "Strategies for Engineered Negligible Senescence" were worthy of debate and verification or whether these ideas were wrong on their face. The panel found that de Grey's proposals for intervening in the aging process, while speculative, often "ran parallel to existing research" and were not "demonstrably wrong."

The Telomerase Revolution

The Enzyme That Holds the Key to Human Aging and Will Soon Lead to Longer, Healthier Lives

Author: Michael Fossel

Publisher: BenBella Books, Inc.

ISBN: 1941631703

Category: Science

Page: 256

View: 6203

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One of Wall Street Journal’s "Best Books for Science Lovers" in 2015 Science is on the cusp of a revolutionary breakthrough. We now understand more about aging—and how to prevent and reverse it—than ever before. In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility. Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging. Twenty years ago, there was still considerable debate of the nature of human aging, with a variety of competing theories in play. But scientific consensus is forming around the telomere theory of aging. The essence of this theory is that human aging is the result of cellular aging. Every time a cell reproduces, its telomeres (the tips of the chromosomes) shorten. With every shortening of the telomeres, the cell’s ability to repair its molecules decreases. It ages. Human aging is the result of the aging of the body’s trillions of cells. But some of our cells don’t age. Sex cells and stem cells can reproduce indefinitely, without aging, because they create telomerase. Telomerase re-lengthens the telomeres, keeping these cells young. The Telomerase Revolution describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to dramatically extend life spans and even reverse human aging. Telomerase-based treatments are already available, and have shown early promise, but much more potent treatments will become available over the next decade. The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.

The Abolition of Aging

The Forthcoming Radical Extension of Healthy Human Longevity

Author: David W Wood

Publisher: Delta Wisdom

ISBN: 9780995494206

Category:

Page: 430

View: 3953

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Within our collective grasp dwells the remarkable possibility of the abolition of biological aging. It's a big "if," but if we decide as a species to make this project a priority, there's around a 50% chance that practical rejuvenation therapies resulting in the comprehensive reversal of aging will be widely available as early as 2040. People everywhere, on the application of these treatments, will, if they wish, stop becoming biologically older. Instead, again if they wish, they'll start to become biologically younger, in both body and mind, as rejuvenation therapies take hold. In short, everyone will have the option to become ageless. The viewpoint just described is a position the author has reached following extensive research, carried out over more than ten years. His research has led him to become a strong supporter of what can be called "the rejuveneering project" a multi-decade cross-disciplinary endeavour to engineer human rejuvenation and thereby enable the choice to abolish aging. But this viewpoint frequently encounters one of two adverse reactions. First, people say that it's not possible that such treatments are going to exist in any meaningful timescale any time soon. In other words, they insist that human rejuvenation can't be done. It's wishful thinking to suppose otherwise, they say. It's bad science. It's naively over-optimistic. It's ignorant of the long history of failures in this field. The technical challenges remain overwhelmingly difficult. Second, people say that any such treatments would be socially destructive and morally indefensible. In other words, they insist that human rejuvenation shouldn't be done. It's essentially a selfish idea, they say - an idea with all kinds of undesirable consequences for societal harmony or planetary well-being. It's an arrogant idea, from immature minds. It's an idea that deserves to be strangled. Can't; shouldn't - this books argues that both these objections are profoundly wrong. It argues instead that rejuvenation is a noble, highly desirable, eminently practical destiny for our species - a "Humanity+" destiny that could be achieved within just one human generation from now. In the author's view, the abolition of aging is set to take its place on the upward arc of human social progress, echoing developments such as the abolition of slavery, the abolition of racism, and the abolition of poverty. This is a discussion with enormous consequences. Changes in the public mood regarding the desirability of rejuveneering could trigger large reallocations of both public and private research expenditure. In turn, these reallocations are likely to have major implications in many areas of public well-being. Clearly, these decisions need to be taken wisely - with decisions being guided by a better understanding of the rich landscape of rejuveneering possibilities. Due to complexities and unknowns, no one can be sure of the outcome of this project. Despite what some rejuvenation enthusiasts may suggest, there's nothing inevitable about the pace of future medical progress. That's why the author gives the probability of success as only around 50%. Although the end outcome remains unclear, the sense of discovery is increasing. The underlying scientific context is changing rapidly. Every day brings its own fresh firehose of news of potential breakthrough medical approaches. In the midst of so much innovation, it behoves us to seek clarity on the bigger picture. To the extent that this book can provide that bigger picture, it will have met at least some of its goals. Armed with that bigger picture, readers of this book will, hopefully, be better placed to find the aspect of the overall rejuveneering project where they can make their best contributions. Together, we can tilt that 50% success probability upwards. The sooner, the better. Note: For advance feedback on this book, see https: //theabolitionofaging.com/.