Genetics

A Molecular Approach

Author: T. A. Brown,Terence A. Brown

Publisher: Garland Pub

ISBN: 9780748743704

Category: Science

Page: 469

View: 7618

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With this revised text, T.A. Brown explains the basic principles of molecular biology and genetics. Included in the third edition are the latest results of genome sequencing projects.

Introduction to Genetics

A Molecular Approach

Author: Terry Brown

Publisher: Garland Science

ISBN: 1136665358

Category: Science

Page: 538

View: 4526

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Genetics today is inexorably focused on DNA. The theme of Introduction to Genetics: A Molecular Approach is therefore the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms and populations). This progression reflects both the basic logic of life and the way in which modern biological research is structured. The molecular approach is particularly suitable for the large number of students for whom genetics is a part of a broader program in biology, biochemistry, the biomedical sciences, and biotechnology. Introduction to Genetics presents the basic facts and concepts with enough depth of knowledge to stimulate students to move on to more advanced aspects of the subject. The book is divided into three parts. Part 1 examines the function of the gene as a unit of biological information. Part 2 studies the role of the gene as a unit of inheritance. And Part 3 explores some of the areas of research that are responsible for the high profile that genetics has in our modern world, from agriculture and industry to medicine and forensics, and the ethical challenges that genetic knowledge imparts.

iGenetics

A Molecular Approach

Author: Peter J. Russell

Publisher: Pearson Higher Ed

ISBN: 0321830288

Category: Medical

Page: 848

View: 7197

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With its modern chapter organization and new “Focus on Genomics” boxes, iGenetics : A Molecular Approach reflects the increasing molecular emphasis in today’s experimental study of genes while helping students develop problem-solving skills and an appreciation for classic experiments. Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help students to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help students visualize and understand processes and concepts that are illustrated in the text.

Genetics

a molecular approach

Author: Laura Livingston Mays

Publisher: Macmillan College

ISBN: N.A

Category: Science

Page: 693

View: 3977

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Molecular Genetics of Yeast

A Practical Approach

Author: John R. Johnston

Publisher: Oxford University Press, USA

ISBN: N.A

Category: Science

Page: 275

View: 3656

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The yeast Saccharomyces cerevisiae is used extensively in academic research as a model eukaryote, and is also one of the most important industrial organisms. It is easy to manipulate, and has a great many parallels with higher organisms, making it ideal for studies in molecular biology, genetics, and biotechnology. This book describes current experimental procedures, written by internationally recognized experts, for working with this organism. Topics covered include DNA isolation, cloning and expression vectors, construction and use of DNA libraries, Ty insertional mutagenesis, high-efficiency transformation, cell-free translation of mRNAs, virus-like particles, and aspects of industrial strains. Molecular Genetics of Yeast: A Practical Approach provides a comprehensive compendium of detailed, clearly presented protocols, with additional practical tips, for all researchers working with this organism.

Primary Immunodeficiency Diseases

A Molecular and Genetic Approach

Author: Hans D. Ochs, MD, Dr.med,C. I. Edvard Smith, PhD,Jennifer M. Puck, MD

Publisher: Oxford University Press

ISBN: 019997103X

Category: Medical

Page: 800

View: 6326

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Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options -- from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy -- this volume will remain an authoritative resource on this increasingly important area.

Genetics

A Molecular Perspective

Author: William S. Klug,Michael R. Cummings

Publisher: Benjamin-Cummings Publishing Company

ISBN: 9780130085306

Category: Science

Page: 691

View: 589

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This book is unique in that it takes a molecular first approach. It starts with DNA and moves through the genetic expression at the molecular level before turning to the more traditional Mendelian and Neomendelian transmission genetics. This book emphasizes what the reader should come to understand, not simply memorize. In addition to topics traditionally covered in genetics, this book provides cutting edge information on Bioinformatics and Proteomics, as well as a chapter on advanced topics in Molecular Genetics.

Genetics: A Conceptual Approach

Author: Benjamin A. Pierce

Publisher: Macmillan

ISBN: 1429232528

Category: Science

Page: 400

View: 435

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Ben Pierce is recognized for his ability to make the complex subject of genetics as accessible as possible, giving students the big picture. By helping students easily identify the key concepts in genetics and by helping them make connections among concepts, Pierce allows students to learn the material with greater ease. W.H. Freeman is proud to introduce the Fourth Edition of Pierce’s Genetics: A Conceptual Approach. Visit the preview site at www.whfreeman.com/pierce4epreview

Genetic Techniques for Biological Research

A Case Study Approach

Author: Corinne A. Michels

Publisher: John Wiley & Sons

ISBN: 9780471899198

Category: Science

Page: 241

View: 3497

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"We must teach students the conceptual and technical approachesused to solve problems in biology. This book will do thissuperbly." - Professor Steve Oliver, School of Biological Sciences,University of Manchester, UK Molecular genetic analysis is the fusion of biochemical and geneticapproaches to investigate the underlying mechanisms of cellularprocesses. These techniques have been developed over the pastdecades by researchers working with model organisms such asbacteriophage, E. coli, Saccharomyces, Drosophila, maize, and morerecently, Arabidopsis and C. elegans. The details of cultivationand crossing of each organism differ, but the theory behindmolecular genetic analysis is the same for all of theseorganisms. Genetic Techniques for Biological Research teaches the methods ofmolecular genetic analysis using a case study approach with theyeast Saccharomyces as the model genetic organism. The toolsavailable for Saccharomyces are the most highly developed, and yetalso most straightforward, of all of the eukaryotic researchorganisms. Furthermore, the theoretical basis of the methods ofmolecular genetic analysis learned using yeast are directlyapplicable to other organisms. The aim is that the reader will develop an appreciation for themolecular genetic method of analysis, and will be able to translatethe critical thinking skills illustrated by the case studies to thereader's own research projects and scientific decisionmaking. Features include: * theoretical overviews of the methods and tools of moleculargenetic analysis * the application of these techniques to published researcharticles * case studies with questions to enable students to developcritical thinking skills Genetic Techniques for Biological Research teaches the theory andpractice of molecular genetic analysis to advanced undergraduatesand graduates studying genetics, genomics, molecular biology andcell biology and is a valuable addition to the reference library ofany research laboratory.

Genetics

a molecular approach

Author: Terence A. Brown

Publisher: CRC Press

ISBN: N.A

Category: Science

Page: 387

View: 2193

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Understanding Genetics

A Molecular Approach

Author: Norman V. Rothwell

Publisher: Wiley-Liss

ISBN: 9780471588221

Category: Medical

Page: 672

View: 4726

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Offers a comprehensive and timely introduction to modern genetics. Focusing on the essential aspects of molecular biology, the editor provides a well-written, accessible presentation of the complex field of molecular genetics.

Human Molecular Genetics

Author: Tom Strachan,Andrew Read

Publisher: Garland Science

ISBN: 1136844074

Category: Science

Page: 782

View: 6853

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Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject. The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

Physiology of the Bacterial Cell

A Molecular Approach

Author: Frederick Carl Neidhardt,John L. Ingraham,Moselio Schaechter

Publisher: Sinauer Associates Incorporated

ISBN: 9780878936083

Category: Science

Page: 506

View: 2346

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Molecular Approach to Cancer Management

Author: Gajanan V. Sherbet

Publisher: Academic Press

ISBN: 0128128976

Category: Medical

Page: 352

View: 7698

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Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and the signal transduction cascades associated with tumor growth, EMT, stem cell maintenance and propagation, and invasion and metastasis. The salient features of the signaling systems that are amenable to targeted manipulation are emphasized to facilitate research and development in the design of novel therapies and for the planning of new trials. This book is the only unique volume with coverage of topics that target therapy. As such, it is a valuable source for cancer researchers, molecular oncologists and members of the biomedical field who are interested in knowing more about molecular approaches to cancer therapy. Covers all relevant topics with a defined aim of targeted therapy Encompasses the basic aspects of cancer invasion and metastasis Discusses signaling systems operating in normal cells and their deregulation in cancer cells Directs attention to the foci in signaling systems that can be targeted with a new and conventional drug-based approach

The Evolution of Molecular Biology

The Search for the Secrets of Life

Author: Kensal Van Holde,Jordanka Zlatanova

Publisher: Academic Press

ISBN: 0128129182

Category: Science

Page: 242

View: 1647

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The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds. Each chapter contains a prologue and epilogue to create continuity and provide a complete framework of molecular biology. This foundational work also functions as a historical and conceptual supplement to many related courses in biochemistry, biology, chemistry, genetics and history of science. In addition, the book demonstrates how the roots of discovery and advances–and an individual’s own research–have grown out of the history of the field, presenting a more complete understanding and context for scientific discovery. Expands on the development of molecular biology from the convergence of two independent disciplines, biochemistry and genetics Discusses the value of molecular biology in a variety of applications Includes research ethics and the societal implications of research Emphasizes the human aspects of research and the consequences of such advances to society

Molecular Genetic Analysis of Populations

A Practical Approach

Author: A. Rus Hoelzel

Publisher: Oxford University Press

ISBN: 9780199636341

Category: Science

Page: 445

View: 3501

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Methods enabling the direct study of genetic variation in natural populations have improved considerably. The new edition explores these updated techniques in DNA analysis and provides a revised and refined laboratory guide to investigating variation in DNA molecules.

The Impact of Plant Molecular Genetics

Author: Bruno W.S. Sobral

Publisher: Springer Science & Business Media

ISBN: 1461598559

Category: Science

Page: 348

View: 3662

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The impact of molecular genetics on plant breeding and, consequently, agri culture, is potentially enonnous. Understanding and directing this potential im pact is crucial because of the urgent issues that we face concerning sustainable agriculture for a growing world population as well as conservation of the world's rapidly dwindling plant genetic resources. This book is largely devoted to the applications of genetic markers that have been developed by the application of molecular genetics to practical problems. These are known as DNA markers. They have gained a certain notoriety in foren sics, but can be used in a variety of practical situations. We are going through a period of accelerated breakthroughs in molecular ge netics. Therefore, the authors of each chapter were encouraged to speculate about both current bottlenecks and the future of their subfields of research. We can cer tainly apply molecular genetic tools and approaches to help resolve crucial ge netic resource problems that face humanity. However, little has been discussed with respect to when or how we should use such tools, nor to who specifically should use them; therefore, social and economic analyses are important in the planning stages of projects that are aimed at practical results.

Gene Cloning and DNA Analysis

An Introduction

Author: T. A. Brown

Publisher: John Wiley & Sons

ISBN: 1119072549

Category: Science

Page: 376

View: 9451

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Known world-wide as the standard introductory text to this important and exciting area, the seventh edition of Gene Cloning and DNA Analysis addresses new and growing areas of research whilst retaining the philosophy of the previous editions. Assuming the reader has little prior knowledge of the subject, its importance, the principles of the techniques used and their applications are all carefully laid out, with over 250 clearly presented four-colour illustrations. In addition to a number of informative changes to the text throughout the book, the chapters on DNA sequencing and genome studies have been rewritten to reflect the continuing rapid developments in this area of DNA analysis: In depth description of the next generation sequencing methods and descriptions of their applications in studying genomes and transcriptomes New material on the use of ChiP-seq to locate protein-binding sites Extended coverage of the strategies used to assemble genome sequences Description of how the Neanderthal genome has been sequenced and what that sequence tells us about interbreeding between Neanderthals and Homo sapiens Gene Cloning and DNA Analysis remains an essential introductory text to a wide range of biological sciences students; including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. It is also a perfect introductory text for any professional needing to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied and taught should have copies available on their shelves.

Molecular Biology

Author: Burton E. Tropp

Publisher: Jones & Bartlett Publishers

ISBN: 0763786632

Category: Science

Page: 1097

View: 7277

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"Molecular Biology: Genes to Proteins is a guide through the basic molecular processes and genetic phenomena of both prokaryotic and eukaryotic cells. Written for the undergraduate and first year graduate students within molecular biology or molecular genetics, the text has been updated with the latest data in the field. It incorporates a biochemical approach as well as a discovery approach that provides historical and experimental information within the context of the narrative."--Publisher.

Mycobacterium

Genomics and Molecular Biology

Author: Tanya Parish,Amanda Brown

Publisher: Horizon Scientific Press

ISBN: 1904455409

Category: Science

Page: 213

View: 1693

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In this book, expert scientists critically review the current and most recent advances in the genomics and molecular biology of mycobacteria. With the focus being on the topical and most relevant aspects, the contributors provide insight into the current understanding of the subject and the future direction of research. Topics covered include strain variation and evolution, hypervirulent strains, electron transport and respiration, lipid biosynthesis, DNA repair, oxygen signaling, sulphur metabolism, protein secretion, the protein kinase family, and much more. This is a valuable reference text for all microbiology laboratories and is essential reading for all scientists and researchers involved with mycobacteria.