Crystallography Made Crystal Clear

A Guide for Users of Macromolecular Models

Author: Gale Rhodes

Publisher: Academic Press

ISBN: 0323137784

Category: Science

Page: 202

View: 5638

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Crystallography Made Crystal Clear is designed to meet the need for an X-ray analysis that is between brief textbook sections and complete treatments. The book provides non-crystallographers with an intellectually satisfying explanation of the principles of how protein models are gleaned from X-ray analysis. The understanding of these concepts will foster wise use of the models, including the recognition of the strengths and weaknesses of pictures or computer graphics. Since proteins comprise the majority of the mass of macromolecules in cells and carry out biologically important tasks, the book will be of interest to biologists. Provides accessible descriptions of principles of x-ray crystallography, built on simple foundations for anyone with a basic science background Leads the reader through clear, thorough, unintimidating explanations of the mathematics behind crystallography Explains how to read crystallography papers in research journals If you use computer-generated models of proteins or nucleic acids for: Studying molecular interactions Designing ligands, inhibitors, or drugs Engineering new protein functions Interpreting chemical, kinetic, thermodynamic, or spectroscopic data Studying protein folding Teaching macromolecule structure,and if you want to read new structure papers intelligently; become a wiser user of macromolecular models; and want to introduce undergraduates to the important subject of x-ray crystallography, then this book is for you.

Crystallography Made Crystal Clear

A Guide for Users of Macromolecular Models

Author: Gale Rhodes

Publisher: Elsevier

ISBN: 9780080455549

Category: Science

Page: 352

View: 3498

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Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs. * Helps readers to understand where models come from, so they don't use them blindly and inappropriately * Provides many visual and geometric models for understanding a largely mathematical method * Allows readers to judge whether recently published models are of sufficiently high quality and detail to be useful in their own work * Allows readers to study macromolecular structure independently and in an open-ended fashion on their own computers, without being limited to textbook or journals illustrations * Provides access to web tools in a format that will not go out of date. Links will be updated and added as existing resources change location or are added

Crystallography Made Crystal Clear

A Guide for Users of Macromolecular Models

Author: Gale Rhodes

Publisher: Academic Press

ISBN: N.A

Category: Science

Page: 269

View: 9655

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This edition explains to graduate students and researchers the basics of crystallography for all macromolecules. This updated version contains 35 percent new material, concentrating on the tremendous advances in the desktop programs used for modeling. New topics include neutron and electron diffraction, protein structure determination by NMR, and recent developments in MAD phasing and high speed data collection in crystallography.

Principles of Protein X-ray Crystallography

Author: Jan Drenth

Publisher: Springer Science & Business Media

ISBN: 1475730926

Category: Science

Page: 341

View: 4298

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New textbooks at all levels of chemistry appear with great regularity. Some fields such as basic biochemistry, organic reaction mechanisms, and chemical thermodynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research that is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive intro ductions to their fields. These should serve the needs of one-semester or one-quarter graduate courses in chemistry and biochemistry. In some cases, the availability of texts in active research areas should help stimulate the creation of new courses. Charles R. Cantor v Preface to the Second Edition Since the publication of the previous edition in 1994, X-ray crystallography of proteins has advanced by improvements in existing techniques and by addition of new techniques.

Outline of Crystallography for Biologists

Author: David Blow

Publisher: Oxford University Press on Demand

ISBN: 0198510519

Category: Medical

Page: 236

View: 9686

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X-ray crystallography is the main method used to determine the structure of biological molecules. X-ray crystallography is explained without maths and reading this text allows biologists to assess the quality and accuracy of biological structures.

Crystal Structure Determination

Author: Werner Massa

Publisher: Springer Science & Business Media

ISBN: 3662042487

Category: Science

Page: 206

View: 6343

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A concise introduction to modern crystal structure determination, emphasizing both the crystallographic background and the successive practical steps. In the theoretical sections, more importance is attached to a good understanding, than to a rigorous mathematical treatment. The most important measuring techniques, including the use of modern area detectors, and the methods of data reduction, structure solution and refinement are discussed from a practical point of view. Special emphasis is put on the ability to recognize and avoid possible errors and traps, and to judge the quality of results.

Protein Crystallography

A Concise Guide

Author: Eaton E. Lattman,Patrick J. Loll

Publisher: JHU Press

ISBN: 0801896843

Category: Science

Page: 152

View: 5038

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The crisp writing style and simple illustrations will provide beginner crystallographers with a guide to the process of unraveling protein structure.

Crystallography

Author: Christian Bök

Publisher: Coach House Books

ISBN: 9781552451199

Category: Science

Page: 157

View: 7994

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Crystallography is the mineral science whose name means 'lucid writing.' Long out of print, but now available again in an elegant revised edition, this extraordinary work of avant-garde literature explores the boundary between science and poetry, suggesting that to write with clarity in either discipline involves the most intense thought, much like an act of 'lucid dreaming.' The book reveals that, within the sediment of everyday language, poems are the crystalline formations. -- Back cover.

Introduction to Crystallography

Author: Donald E. Sands

Publisher: Courier Corporation

ISBN: 0486136809

Category: Science

Page: 192

View: 2307

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Clear, concise explanation of logical development of basic crystallographic concepts. Topics include crystals and lattices, symmetry, x-ray diffraction, and more. Problems, with answers. 114 illustrations. 1969 edition.

Biomolecular Crystallography

Principles, Practice, and Application to Structural Biology

Author: Bernhard Rupp

Publisher: Garland Science

ISBN: 1134064195

Category: Science

Page: 800

View: 6587

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Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography._ Deftly illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. It distills key concepts for understanding the practice and analysis of protein crystal structures and contains examples of biologically-relevant molecules, complexes, and drug target structures. Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics.

Biophysical Techniques

Author: Iain Campbell

Publisher: Oxford University Press

ISBN: 0199642141

Category: Medical

Page: 353

View: 6161

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Biophysical Techniques explains in a readily-accessible way the basics of the various biophysical methods available so students can understand the principles behind the different methods used, and begin to appreciate which tools can be used to probe different biological questions, and the pros and cons of each.

Encyclopedic Dictionary of Polymers

Author: Jan W. Gooch

Publisher: Springer Science & Business Media

ISBN: 1441962468

Category: Reference

Page: 1016

View: 9319

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This is the first complete book of polymer terminology ever published. It contains more than 7,500 polymeric material terms. Supplementary electronic material brings important relationships to life, and audio supplements include pronunciation of each term.

Theories and Techniques of Crystal Structure Determination

Author: Uri Shmueli

Publisher: Oxford University Press

ISBN: 019921350X

Category: Science

Page: 269

View: 9413

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The book is a detailed but concise exposition of crystal structure determination at a graduate level. Discussions range from geometrical principles of crystallography, through relevant experimental methods, to techniques of reliable and accurate determination of crystal structures.

Crystal Structure Analysis for Chemists and Biologists

Author: Jenny P. Glusker,Mitchell Lewis,Miriam Rossi

Publisher: John Wiley & Sons

ISBN: 9780471185437

Category: Science

Page: 854

View: 2152

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The fields of structural chemistry and biochemistry have blossomed in the last seventy years since X-ray diffraction was discovered in 1912. Dorothy Hodgkin, who obtained a Nobel Prize in 1965 for her X-ray diffraction work wrote 'a great advantage of X-ray analysis as a method of chemical structure analysis is its power to show some totally unexpected and surprising structure with, at the same time, complete certainty.' The results of all X-ray diffraction studies are used by chemists and buiochemists but these scientists need to be able to appreciate the significance and extent to which these results may be used. A number of books written for practicing crystallographers cover the theory and applications of X-ray diffraction, but few are of real practical use to non-specialists. In 'Crystal Structure Analysis for Biologists and Chemists', the general principles of crystal structure are presented in a highly readable way. The book of Glusker, who is internationally renowned, provides good coverage of theory, including data and understanding their significance.

Crystal Clear

The Autobiographies of Sir Lawrence and Lady Bragg

Author: Patience Thomson

Publisher: Oxford University Press, USA

ISBN: 0198744307

Category: BIOGRAPHY & AUTOBIOGRAPHY

Page: 448

View: 9317

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The main body of this book contains the hitherto unpublished autobiographies of both William Lawrence Bragg, an innovative scientist who won the Nobel Prize for Physics in 1915, and his wife, Alice, a Mayor of Cambridge and National Chairman of Marriage Guidance. Their autobiographies give unusual insights into the lives and times of two distinguished people and the real personalities behind their public appearance.

Crystal Structure Analysis

Principles and Practice

Author: Alexander J Blake,William Clegg

Publisher: Oxford University Press

ISBN: 019921946X

Category: Science

Page: 387

View: 6875

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By choosing an approach that avoids undue emphasis on the mathematics involved, this book gives practical advice on topics such as growing crystals, solving and refining structures, and understanding and using the results.

Introduction to Protein Structure

Author: Carl-Ivar Brändén,John Tooze

Publisher: Taylor & Francis

ISBN: 0815323050

Category: Medical

Page: 410

View: 4748

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This new edition gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context, illustrated in colour to illuminate the structural principles described in the text.

The Cell Cycle

Principles of Control

Author: David Owen Morgan

Publisher: New Science Press

ISBN: 0878935088

Category: Science

Page: 297

View: 1863

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The Cell Cycle: Principles of Control provides an engaging insight into the process of cell division, bringing to the student a much-needed synthesis of a subject entering a period of unprecedented growth as an understanding of the molecular mechanisms underlying cell division are revealed.

Crystal structure analysis

a primer

Author: Jenny Pickworth Glusker,Kenneth N. Trueblood

Publisher: N.A

ISBN: N.A

Category: Science

Page: 269

View: 9856

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This practical guide explains how and why the architecture of molecules can be determined by analysis of the diffraction patterns produced by X-ray crystallography. Thoroughly illustrated, it is intended for nonspecialists who want to understand the fundamentals of this widely used method ofstructure determination. The new second edition has been revised and expanded to take account of the many recent advances in the field.